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Image Search Results
Journal: Pharmaceutics
Article Title: In Silico Studies to Support Vaccine Development
doi: 10.3390/pharmaceutics15020654
Figure Lengend Snippet: Results from Phase 2 (Compilation of all in silico models to support vaccine development).
Article Snippet: Cancer vaccine , PBPK , To represent the distribution of certain molecules eluted through a 3D-printed implantable system named ‘NICHE’ , The NICHE platform aims to study immunomodulation for cell therapeutics and cancer vaccines. It is a two-compartment model composed of a vascularized tissue reservoir and a surrounding refillable drug reservoir. The PBPK model was able to recapitulate the biodistribution of the molecules in scope, and together with NICH, they represent a flexible, adaptable platform to investigate
Techniques: In Silico, Software, Vaccines, Injection, Adjuvant, In Vivo, Formulation, Infection, Bioprocessing, Virus, Emulsion, Drug discovery, Neutralization, Concentration Assay, Biomarker Discovery, Construct, Binding Assay, Diffusion-based Assay, Recombinant, Immunopeptidomics, Solubility, Cloning